Family name Papayannopoulos (Papayannopoulos 
) , across the world, is a very rare cognomen. The cognomen Papayannopoulos is habitual in Greece, where it is a rare surname, South Africa, where it is a very rare surname, and Canada. In absolute terms, this name is the most popular in Greece, South Africa, and the United States.
| VARIANT | COUNTRY |
|---|---|
| Papayannopoulos | Canada, South Africa, Greece, United States, Brazil |