Cognomen Leyssius (Leyssius 
) , throughout the world, is a very rare family name. The family name Leyssius is habitual in Netherlands, where it is a very rare surname, and the United States, where it is an extremely rare surname.
| VARIANT | COUNTRY |
|---|---|
| Leyssius | United States, Netherlands |
|
emile henri florent leyssius (b. 1849) |
|
| barbara leyssius |
|