Last name Hupfer (Hupfer 
) , all over the world, is quite a rare surname. The cognomen Hupfer is characteristic of Germany, where it is quite a rare surname, Cyprus, and Austria, where it is a rare surname. Measured by absolute frequency, it is the most numerous in Germany, the United States, and Austria.
| VARIANT | COUNTRY |
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| Hupfer | Germany, Switzerland, United States, Austria, Brazil |
| andreas hupfer DE (b. 1721) |
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| friedrich wilhelm hupfer DE (b. 1820) |
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| franz ferdinand hupfer DE (b. 1827) |
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| karl hupfer (b. 1862) |
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| konrad hupfer German officer and Knight's Cross recipient (1911-1944), DE (b. 1911) |
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| heinz hupfer German actor (1922-1991), DE (b. 1922) |
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| peter hupfer DE (b. 1933) |
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| jean-michel hupfer French politician, FR (b. 1953) |
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| giorgio hupfer (b. 1958) |
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| isabelle hupfer FR (b. 1967) |
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| kyle hupfer college basketball player (1992–1993) North Carolina-Greensboro |
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| michael hupfer researcher (ORCID 0000-0002-8878-1045) |
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| maximilian l hupfer researcher |
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| thomas hupfer Dr. rer. nat. Friedrich-Alexander-Universität Erlangen-Nürnberg 2001 |
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| sarah hupfer German association football player, DE (b. 1988) |
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