Surname Gugino (Gugino 
) , throughout the world, is quite a rare cognomen. The surname Gugino is characteristic of Italy, where it is a rare surname, the United States, and Argentina, where it is a very rare surname.
| VARIANT | COUNTRY |
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| Gugino | Argentina, United States, Germany, Italy, Canada |
| giuseppe gugino IT (b. 1843) |
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| giuseppe gugino (b. 1843) |
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| edoardo gugino Italian mathematician (1895-1967), IT (b. 1895) |
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| eduardo gugino IT (b. 1895) |
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carla gugino American actress, US (b. 1971) |
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| charles gugino lit the Olympic flame in Lake Placid in 1980 |
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| anthony gugino college basketball player (2007–2007) Long Island University |
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| carl f. gugino American orthodontist |
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| tony gugino American basketball player, US (b. 1986) |
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