Cognomen Drenthe (Drenthe 
, Drente ) , worldwide, is a rare last name. The cognomen Drenthe is characteristic of Western Europe, particularly Netherlands, where it is quite a rare surname, Belgium, where it is a very rare surname, and Germany. Measured by absolute frequency, it is the most numerous in Netherlands, the United States, and Germany.
| VARIANT | COUNTRY |
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| Drenthe | Australia, Netherlands, Germany, United States, Poland |
| Drente | Germany |
| balderik van teisterbant graaf van salland en drenthe (945-1021) (b. 945) |
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| balderich von drenthe count of the Holy Roman empire, DE (b. 965) |
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| albertus jacobus sap van drenthe NL (b. 1835) |
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eugene drenthe Surinamese poet and playwright, SR (b. 1925) |
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| lou drenthe SR (b. 1901) |
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royston drenthe Dutch professional footballer, NL (b. 1987) |
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| esther drenthe Dutch actress, NL (b. 1964) |
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| giovanni drenthe Surinamese footballer, SR (b. 1990) |
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| klebert drenthe SR (b. 1983) |
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